Using gold nanoparticles to detect single-nucleotide polymorphisms: toward liquid biopsy

• María Sanromán Iglesias and
• Marek Grzelczak

Beilstein J. Nanotechnol. 2020, 11, 263–284, doi:10.3762/bjnano.11.20

• -stabilized gold nanoparticles of 13 nm in diameter (Figure 3a). A target oligonucleotide (24–30 bases) that was complementary to the single-stranded DNA (ssDNA) of both types of nanoparticles induced an aggregation through hybridization. The main advantage of this method is the low risk of false positives

• target. c) Colorimetric assay based on unmodified nanoparticles: Single-stranded DNA (ssDNA) stabilizes gold nanoparticles against salt-induced aggregation, while in the presence of double-stranded DNA (dsDNA) particles undergo aggregation. Discrimination of SNPs by means of the kinetics of particle

Molecular architectonics of DNA for functional nanoarchitectures

• Debasis Ghosh,
• Lakshmi P. Datta and
• Thimmaiah Govindaraju

Beilstein J. Nanotechnol. 2020, 11, 124–140, doi:10.3762/bjnano.11.11

• sequence specificity, molecular recognition properties, and the formation of regular and defined structures of DNA made it possible to custom the design and to engineer a range of molecular architectures [5][6][7][8][9]. In DNA, two polydeoxyoligonucleotides (single-stranded DNA, ssDNA) are held together

Single pyrimidine discrimination during voltage-driven translocation of osmylated oligodeoxynucleotides via the α-hemolysin nanopore

• Yun Ding and
• Anastassia Kanavarioti

Beilstein J. Nanotechnol. 2016, 7, 91–101, doi:10.3762/bjnano.7.11

• above detection limits, may be further optimized, and clear the way for nanopore-based sequencing using osmylated DNA. Keywords: DNA sequencing; α-hemolysin; ion-channel measurements; nanopore; osmium tetroxide bipyridine; osmylated oligos; osmylation; single-stranded DNA (ssDNA); Introduction

DNA–melamine hybrid molecules: from self-assembly to nanostructures

• Rina Kumari,
• Shib Shankar Banerjee,
• Anil K. Bhowmick and
• Prolay Das

Beilstein J. Nanotechnol. 2015, 6, 1432–1438, doi:10.3762/bjnano.6.148

• ]. However, the directionality of the single-stranded DNA (ssDNA) sequences obtained through a DNA synthesizer is limited only to the terminal positions. This could limit further DNA extension in both directions. As a recent trend, DNA–organic molecule hybrid structures are being produced post-synthesis to

Non-covalent and reversible functionalization of carbon nanotubes

• Antonello Di Crescenzo,
• Valeria Ettorre and
• Antonella Fontana

Beilstein J. Nanotechnol. 2014, 5, 1675–1690, doi:10.3762/bjnano.5.178

• , the most representative one is DNA and different examples of non-covalently functionalized SWCNTs with DNA have been published. While double-stranded DNA (dsDNA), being more rigid, displayed a less efficient wrapping, single-stranded DNA (ssDNA) has been used to disperse CNTs or to separate and purify